Methicillin-resistant Staphylococcus aureus (MRSA): identification and susceptibility testing techniques.

Autors:	Wanda Reygaert
Idioma:	Eng.
Data:	2009-06-18
Revista:	Clinical laboratory science : journal of the American Society for Medical Technology (0894-959X)
Lliurament:	Clin Lab Sci. 2009 ;22(2):120-4
Abstract:	Many traditional techniques are useful for identification of MRSA strains, including techniques for detection of penicillin-resistance, such as the nitrocefin disk. Techniques for assessing methicillin-resistance vary from growth on special media or at a lower temperature, to detection of the mecA gene by manual (latex agglutination) and automated (PCR) methods. Technique development is now geared toward making MRSA identification more rapid. Real-time PCR has sped MRSA detection, but can be costly. Resistance to other drugs is also an issue. Clindamycin resistance may need to be induced, so a special disk diffusion test can be performed. Vancomycin resistance is becoming an issue, so alternative drugs need to be identified. Drugs that are currently available for MRSA infections include: daptomycin, linezolid, quinupristin/dalfopristin, and tigecycline. Drugs that are in the development phase include: ceftobiprole, dalbavancin, oritavancin, and telavancin. These drugs provide a promising arsenal against MRSA.
Copyright:	Clinical laboratory science : journal of the American Society for Medical Technology Oakland University, School of Health Sciences, Medical Laboratory Science Program, Rochester, Michigan 48309, USA. reygaert oakland.edu
Full text:	DOI - Clinical laboratory science : journal of the American Society for Medical Technology (DOI) EBSCO - HTML (amb subscripció) ProQuest Information and Learning - HTML (amb subscripció)
Temes:	Anti-Bacterial Agents, Bacterial Proteins, Culture Media, Drug Resistance, Multiple, Bacterial, Humans, Latex Fixation Tests, Methicillin Resistance, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Polymerase Chain Reaction, Staphylococcal Infections