Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia.

Autors:Arthur A M Wilde, Zahurul A Bhuiyan, Lia Crotti, Mario Facchini, Gaetano M De Ferrari, Thomas Paul, Chiara Ferrandi, Dave R Koolbergen, Attilio Odero, Peter J Schwartz
Idioma:Eng.
Data:08-05-2008
Revista:The New England journal of medicine (1533-4406)
Lliurament:N Engl J Med. 2008 May;358(19):2024-9


Abstract:



Catecholaminergic polymorphic ventricular tachycardia is a potentially lethal disease characterized by adrenergically mediated ventricular arrhythmias manifested especially in children and teenagers. Beta-blockers are the cornerstone of therapy, but some patients do not have a complete response to this therapy and receive an implantable cardioverter-defibrillator (ICD). Given the nature of catecholaminergic polymorphic ventricular tachycardia, ICD shocks may trigger new arrhythmias, leading to the administration of multiple shocks. We describe the long-term efficacy of surgical left cardiac sympathetic denervation in three young adults with catecholaminergic polymorphic ventricular tachycardia, all of whom had symptoms before the procedure and were symptom-free afterward.

Copyright:The New England journal of medicine

University of Amsterdam, Amsterdam. a.a.wilde@amc.uva.nl
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Temes:Adolescent, Catecholamines, Defibrillators, Implantable, Electrocardiography, Female, Follow-Up Studies, Heart, Humans, Male, Sympathectomy, Tachycardia, Ventricular
 
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The New England journal of medicine