The trigeminal trophic syndrome: an unusual cause of nasal ulceration.

Authors:Seetha U Monrad, Jeffrey E Terrell, David M Aronoff
Language:Eng.
Date:2004-05-21
Journal:Journal of the American Academy of Dermatology (0190-9622)
Release:J Am Acad Dermatol. 2004 Jun;50(6):949-52


Abstract:



Trigeminal trophic syndrome (TTS) is an unusual complication after peripheral or central damage to the trigeminal nerve, characterized by anesthesia, paresthesias, and ala nasi ulceration. We describe a patient with classic TTS after trigeminal rhizotomy who underwent several extensive evaluations for nasal ulceration and received prolonged immunosuppressive therapy for a presumed autoimmune disorder before the correct diagnosis was made. An understanding of the predisposing factors and clinical presentation of TTS is important to ensure a timely diagnosis of this difficult-to-treat illness. Differentiation of TTS from malignancy, infection, or vasculitis is possible on the basis of clinical history, tissue biopsy, and serologic evaluation.

Copyright:Journal of the American Academy of Dermatology

Department of Internal Medicine, University of Michigan Health Systems, Ann Arbor, Michigan, USA.
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Terms:Female, Humans, Middle Aged, Nose Diseases, Postoperative Complications, Syndrome, Trigeminal Nerve, Ulcer
 
Journal of the American Academy of Dermatology