The authors report a very rare case of a vestibular schwannoma with an infiltrate of monoclonal plasma cells. A 45-year-old woman underwent routine excision of a presumed vestibular schwannoma.
Histological analysis revealed the presence of a distinct lambda light chain restricted plasma cell population within the schwannoma.
The light chain restriction and polymerase chain reaction-demonstrated monoclonality of the plasma cell population suggested the co-occurrence of a plasma cell neoplasm within a schwannoma. A search for systemic disease of plasma cell origin was unremarkable. A search of the literature suggests that this is the first report of such an occurrence.
2009-09-02
Eng.
Journal of Neurosurgery
Department of Neurosurgery, Royal Free Hospital, London, UK. joshuaplaut [at] googlemail.com
J Neurosurg. 2009 Sep;111(3):509-11
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