The high specificity and positive predictive value for the evaluation of tumor response with PET2 and PET3 might avoid unnecessary salvage surgery in patients with a CR. In contrast to PET3, the sensitivity of PET 2 was low, and the difference in OS between the CR and NCR groups was not significantly different. Therefore, the evaluation of the tumor response with FDG-PET at 4 months after RT completion cannot be replaced by FDG-PET during RT at 47 Gy.
Department of Nuclear Medicine, Universitair Ziekenhuis Brussel, Brussels, Belgium. ceulemansgaetane [at] yahoo.com
Int J Radiat Oncol Biol Phys. 2011 Nov;81(4):938-42
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