Short-term effects of inhalative tiotropium/formoterol/budenoside versus tiotropium/formoterol in patients with newly diagnosed chronic obstructive pulmonary disease requiring surgery for lung cancer: a prospective randomized trial.

Abstract

Both therapies resulted in an improvement of lung function.

There is benefit from adding inhalative budenoside to tiotropium and formoterol in terms of an improvement in FEV1 and the severity of COPD. These beneficial results might lead to less pulmonary complications in the postoperative period.

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Subjects

• Administration, Inhalation
• Adrenal Cortex Hormones
• Aged
• Airway Resistance
• Bronchodilator Agents
• Budesonide
• Carcinoma, Non-Small-Cell Lung
• Drug Combinations
• Drug Therapy, Combination
• Epidemiologic Methods
• Ethanolamines
• Forced Expiratory Volume
• Humans
• Lung Neoplasms
• Middle Aged
• Plethysmography, Whole Body
• Pneumonectomy
• Preoperative Care
• Pulmonary Disease, Chronic Obstructive
• Scopolamine Derivatives
• Smoking Cessation
• Treatment Outcome
• Vital Capacity

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• Effects of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPD. (2006-03-15)
• Multidetector-row computed tomography assessment of adding budesonide/formoterol to tiotropium in patients with chronic obstructive pulmonary disease. (2013-01-20)
• The additive effect of theophylline on a combination of formoterol and tiotropium in stable COPD: a pilot study. (2007-04-06)
• Safety and Efficacy of 12-Week or Longer Indacaterol Treatment in Moderate-to-Severe COPD Patients: A Systematic Review. (2013-01-10)
• Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease. (2012-09-12)
• Energy expenditure and impact of bronchodilators in COPD patients. (2010-09-06)
• Comparison of tiotropium plus formoterol to tiotropium alone in stable chronic obstructive pulmonary disease: a meta-analysis. (2011-01-28)
• Bronchodilator response to formoterol after regular tiotropium or to tiotropium after regular formoterol in COPD patients. (2005-04-12)

Authors

• Servet Bölükbas
• Michael Eberlein
• Jennifer Eckhoff
• Joachim Schirren

Publication date

2011-05-09

Journal

Journal topics

• Cardiac Surgical Procedures
• Thoracic Surgery

Language

Eng.

Copyright

Department of Thoracic Surgery, Dr.-Horst-Schmidt-Klinik, Wiesbaden, Germany. Dr.Bolukbas [at] gmx.de

Release reference

Eur J Cardiothorac Surg. 2011 Jun;39(6):995-1000

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