Emotional-processing biases occur in amygdala responses to sad faces presented below the level of conscious awareness in dMDD or rMDD individuals and to happy faces in HCs. By influencing the salience of social stimuli, mood-congruent processing biases in the amygdala may contribute to dysfunction in conscious perceptions and social interactions in MDD. Our data suggest, however, that the negative bias resolves and a positive bias develops in patients with MDD during selective serotonin reuptake inhibitor treatment.
Archives of general psychiatry
National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.
Arch Gen Psychiatry. 2010 Nov;67(11):1128-38
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