It is feasible to conduct a prehospital randomized controlled trial with HSD for treatment of blunt trauma patients with head injuries; however, consent for neurofunctional outcomes in this cohort is problematic and threatens the feasibility of definitive trials using these potentially meaningful end points.
Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Ontario, Canada. morrisonl [at] smh.ca
J Crit Care. 2011 Aug;26(4):363-72
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