Inflammatory optic neuritis (ON) represents a frequent clinical situation in neurology and ophthalmology.
When MRI and CSF analysis are normal, ON is considered idiopathic with a suspected viral etiology. However, in several cases either a recurrence or a myelitis may occur.
In the first case, it is relapsing inflammatory optic neuritis (RION) and in the second case it is neuromyelitis optica (NMO). Nevertheless, predictive criteria of a recurrence or an extension of the disease to spinal cord remains unknown, excepted for anti-NMO IgG antibodies which are probably highly specific for a future evolution to NMO. In the present paper, the authors successively present the two clinical situations (RION and NMO) and attempt to summarize diagnostic and prognostic criteria.
2010-12-14
Fre.
Revue neurologique
Service de neurologie, CHU de Strasbourg, 1, place de l'hôpital, 67091 Strasbourg cedex, France. jerome.de.seze [at] chru-strasbourg.fr
Rev Neurol (Paris). 2010 Dec;166(12):966-9
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