IL-12 and IL-18 levels in serum and gingival tissue in aggressive and chronic periodontitis.

Abstract

Our results showed higher levels of IL-12 in gingival tissue and serum of patients with aggressive periodontitis, and IL-18 was elevated in the serum of CP patients.

The patterns of IL-12 and IL-18 are different in chronic and aggressive periodontitis; this finding suggests distinctive mechanisms of immunopathogenesis between these forms of periodontitis.

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Subjects

• Adolescent
• Adult
• Age Factors
• Aggressive Periodontitis
• Biopsy
• Chronic Periodontitis
• Dental Plaque Index
• Female
• Gingiva
• Gingival Hemorrhage
• Humans
• Interleukin-12
• Interleukin-18
• Male
• Middle Aged
• Periodontal Attachment Loss
• Periodontal Index
• Periodontal Pocket
• Periodontium
• Young Adult

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Authors

• P E Sánchez-Hernández
• A L Zamora-Perez
• M Fuentes-Lerma
• C Robles-Gómez
• R P Mariaud-Schmidt
• C Guerrero-Velázquez

Publication date

2011-06-01

Journal

Journal topics

• Mouth Diseases

Language

Eng.

Copyright

Oral diseases

Laboratorio de Inmunología, División de Disciplinas, Básicas, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, México.

Release reference

Oral Dis. 2011 Jul;17(5):522-9

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