Randomized controlled trial of forward-planned intensity modulated radiotherapy for early breast cancer: interim results at 2 years.

Abstract

IMRT can lead to a significant reduction in telangiectasia at comparatively early follow-up of only 2 years after RT completion.

An important component of breast induration and shrinkage will actually result from the surgery and not from the RT. Surgical cosmesis is an important determinant of overall cosmesis and could partially mask the longer term benefits of IMRT at this early stage.

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Subjects

• Adult
• Aged
• Aged, 80 and over
• Algorithms
• Breast
• Breast Diseases
• Breast Neoplasms
• Confidence Intervals
• Esthetics
• Female
• Humans
• Medical Illustration
• Middle Aged
• Neoplasm Staging
• Odds Ratio
• Organ Size
• Photography
• Radiotherapy Planning, Computer-Assisted
• Radiotherapy, Intensity-Modulated
• Telangiectasis
• Tumor Burden

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Authors

• Gillian C Barnett
• Jennifer S Wilkinson
• Anne M Moody
• Charles B Wilson
• Nicola Twyman
• Gordon C Wishart
• Neil G Burnet
• Charlotte E Coles

Publication date

2012-01-16

Journal

Journal topics

• Radiobiology

Language

Eng.

Copyright

Department of Oncology, University of Cambridge, Cambridge University Hospitals, National Health Service Foundation Trust, Cambridge, United Kingdom.

Release reference

Int J Radiat Oncol Biol Phys. 2012 Feb;82(2):715-23

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