Semen analysis by electron and fluorescence microscopy in a case of partial hydatidiform mole reveals a high incidence of abnormal morphology, diploidy, and tetraploidy.

Abstract

Semen analysis revealed a high incidence of abnormal morphology and increased diploidy.

It may be important to perform FISH testing, to verify increased diploidy in sperm, in men whose wives have had partial moles.

These couples could be informed of the option to have preimplantation genetic diagnosis as a means to distinguish between diploid and triploid embryos arising from fertilization of a haploid egg by diploid sperm.

Full Text

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Subjects

Authors

Publication date

2011-05-23

Journal

Fertility and sterility
Fertil Steril (1556-5653)

Journal topics

Language

Eng.

Copyright

Fertility and sterility

Section of Reproductive Medicine, First Department of Obstetrics and Gynaecology, Aristotle University Medical School, Papageorgiou General Hospital, Thessaloniki, Greece. katerinachatzime [at] hotmail.com

Release reference

Fertil Steril. 2011 Jun;95(7):2430.e1-5