Wnt pathway activation, cell migration, and lipid uptake is regulated by low-density lipoprotein receptor-related protein 5 in human macrophages.

Abstract

These results demonstrate the involvement of LRP5 in the innate inflammatory reaction to lipid infiltration in atherosclerosis.

Full Text

• DOI - European heart journal (DOI)
• Swets Information Services - full-text online
• Ovid Technologies, Inc. - full-text online
• OhioLINK Electronic Journal Center - full-text online
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• EBSCO - full-text online

Subjects

• Apoptosis
• Atherosclerosis
• Bone Morphogenetic Protein 2
• Cell Differentiation
• Cell Movement
• Cell Survival
• Cells, Cultured
• Foam Cells
• Humans
• Lipid Metabolism
• Lipoproteins, LDL
• Low Density Lipoprotein Receptor-Related Protein-5
• Macrophages
• Monocytes
• Osteopontin
• RNA, Messenger
• RNA, Small Interfering
• Wnt Signaling Pathway

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Authors

• Maria Borrell-Pagès
• July Carolina Romero
• Oriol Juan-Babot
• Lina Badimon

Publication date

2011-11-15

Journal

Journal topics

• Cardiology

Language

Eng.

Copyright

European heart journal

Cardiovascular Research Center, CSIC-ICCC, Hospital de la Santa Creu i Sant Pau, UAB, Barcelona, Spain.

Release reference

Eur Heart J. 2011 Nov;32(22):2841-50

Related books

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