Necrolytic migratory erythema (NME) is a skin condition historically associated with pancreatic glucagonomas.
Rarely it occurs in the absence of a pancreatic tumor, which has been described as pseudoglucagonoma syndrome.
We describe a woman with a metastatic neuroendocrine tumor who developed NME 6 years after diagnosis of the tumor.
Her laboratory data revealed essential fatty acid deficiency and a high level of glucagon.
Although the pathogenesis of NME is not completely understood, zinc, essential amino acid, and fatty acid deficiencies have all been postulated as possible causative factors.
2011-03-21
Eng.
Cutis; cutaneous medicine for the practitioner
Department of Dermatology, Mount Sinai School of Medicine, New York, New York, USA. margarita.lolis [at] mssm.edu
Cutis. 2011 Feb;87(2):78-80
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