This study showed, that already 100 mmHg upregulates the expression of several adhesion molecules in pig veins followed by increased adhesion of leukocytes. Therefore, our data demonstrate the advantage of arteries for CABG, and that new therapeutic strategies are urgently necessary to protect vein grafts either physically or pharmacologically if arteries are not available for CABG.
The Journal of cardiovascular surgery
Department of Congenital and Pediatric Cardiac Surgery, Children Hospital, Clinical Research Laboratory, University Hospital Tuebingen, Germany.
J Cardiovasc Surg (Torino). 2011 Apr;52(2):251-9
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