Low-grade gliomas in children ≤5 years old with tumors in the optic pathway/hypothalamus are more likely to progress, but this does not confer worse OS because of the success of salvage therapy.
When GTR is not achieved, adjuvant RT improves FFP but not OS. Routine adjuvant RT can be avoided and instead reserved as salvage.
2011-10-31
Eng.
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI, USA. koh2 [at] partners.org
Int J Radiat Oncol Biol Phys. 2011 Nov;81(4):e481-8
© Galenicom 1999-2013