Systemic administration of reovirus (Reolysin) inhibits growth of human sarcoma xenografts.

Abstract

These results suggest that Reolysin alone or in combination with other cytotoxic agents may be effective therapy in pediatric sarcomas.

Full Text

• DOI - Cancer (DOI)
• John Wiley & Sons, Inc. - full-text online
• Swets Information Services - full-text online
• OhioLINK Electronic Journal Center - full-text online
• EBSCO - full-text online

Subjects

• Animals
• Antineoplastic Agents
• Cell Line, Tumor
• Cell Proliferation
• Cell Survival
• Combined Modality Therapy
• Humans
• Mice
• Mice, Nude
• Mice, SCID
• Neoplasm Transplantation
• Oncolytic Virotherapy
• Reoviridae
• Sarcoma
• Transplantation, Heterologous

Authors

• Pooja Hingorani
• Wendong Zhang
• Juan Lin
• Laibin Liu
• Chandan Guha
• E Anders Kolb

Publication date

2011-04-07

Journal

Journal topics

• Neoplasms

Language

Eng.

Copyright

Cancer

Department of Pediatric Hematology/Oncology, Phoenix Children's Hospital, Phoenix, Arizona 85016, USA. phingorani [at] phoenixchildrens.com

Release reference

Cancer. 2011 Apr;117(8):1764-74

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