Novel fasting glucose loci identified in genome-wide association studies of adults are associated with altered fasting glucose levels in healthy children and adolescents with effect sizes comparable to adults.
In nondiabetic adults, fasting glucose changes little over time, and our results suggest that age-independent effects of fasting glucose loci contribute to long-term interindividual differences in glucose levels from childhood onwards.
2011-05-27
Eng.
Medical Research Council Epidemiology Unit, Addenbrooke’s Hospital,Institute of Metabolic Science, Cambridge, U.K.
Diabetes. 2011 Jun;60(6):1805-12
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