Overall, similar protein changes were observed in schizophrenia and bipolar disorder and for the first time indicate that the most prominent proteomic changes occur within the hippocampus in cornu ammonis regions 2 and 3. The cytoskeletal protein septin 11 and the cellular trafficking process of clathrin-mediated endocytosis are implicated by our study.
Archives of general psychiatry
Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.
Arch Gen Psychiatry. 2011 May;68(5):477-88
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