Central motor conduction studies and diagnostic magnetic resonance imaging in children with severe primary and secondary dystonia.


Abstract

This study provides new CMCT data for children with severe primary and secondary dystonia.

Over 50% of children with evidence of periventricular white-matter damage from magnetic resonance imaging had normal CMCT, challenging traditional pathophysiological models.

This is consistent with recent diffusion tensor imaging in children with periventricular white-matter damage, showing disruption of sensory connections rather than corticospinal tract damage. CMCT helps refine our understanding of imaging changes in complex motor disorders of childhood.


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