HCl injection (pH 4.0) into the gluteus can induce plantar hypersensitivity and urinary frequency for up to 2 weeks after the injection, suggesting that somatic (gluteus)-to-visceral (bladder) cross-sensitization might underlie bladder hypersensitivity in patients with FMS. Moreover, intervention at specific tender points outside the bladder could be effective in treating urinary frequency because lidocaine injection into the gluteus normalized bladder function in FMS rats for up to 2 weeks.
Department of Urology, Jikei University School of Medicine, Tokyo, Japan. a-furuta [at] rf7.so-net.ne.jp
BJU Int. 2012 Jan;109(2):306-10
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