Identification and assessment of new biomarkers for colorectal cancer with serum N-glycan profiling.

Abstract

The current results indicated that the N-glycan markers based diagnostic models are new, valuable, noninvasive alternatives for identifying CRC. The authors concluded that decreased fucosyltransferase may be responsible for decreased levels of total core-fucosylated modification in both tissues and serum from patients with CRC.

Full Text

• DOI - Cancer (DOI)
• John Wiley & Sons, Inc. - full-text online
• Swets Information Services - full-text online
• OhioLINK Electronic Journal Center - full-text online
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Subjects

• Adenoma
• Case-Control Studies
• Colorectal Neoplasms
• Female
• Follow-Up Studies
• Humans
• Lectins
• Male
• Middle Aged
• Polysaccharides
• Prognosis
• Prospective Studies
• Retrospective Studies
• Reverse Transcriptase Polymerase Chain Reaction
• Tumor Markers, Biological

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Authors

• Yun-Peng Zhao
• Can-Ping Ruan
• Hao Wang
• Zhi-Qian Hu
• Meng Fang
• Xing Gu
• Jun Ji
• Jin-Yan Zhao
• Chun-Fang Gao

Publication date

2012-01-23

Journal

Journal topics

• Neoplasms

Language

Eng.

Copyright

Cancer

Department of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.

Release reference

Cancer. 2012 Feb;118(3):639-50

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