The D phenotype distribution in G2 resembles that in Europeans while the frequencies in G1 account for the Amerindian and African genetic contribution.
The genotyping strategy described here is suitable to study D variants in the overall population and could allow a better use of the few available D- units and a rational administration of anti-D immunoprophylaxis.
The results also show that weak D Type 1 alleles do not exclusively segregate with a Ce allele, as assumed until present.
2012-01-13
Eng.
Laboratorio de Inmunohematología e Inmunogenética, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.
Transfusion. 2012 Feb;52(2):389-96
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