Effects of bedtime very low dose cyclobenzaprine on symptoms and sleep physiology in patients with fibromyalgia syndrome: a double-blind randomized placebo-controlled study.

Abstract

Bedtime VLD CBP treatment improved core FM symptoms.

Nights with CAP(A2+A3(Norm)) ≤ 33% may provide a biomarker for assessing treatment effects on nonrestorative sleep and associated fatigue and mood symptoms in persons with FM.

Full Text

• DOI - The Journal of rheumatology (DOI)
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• HighWire Press - full-text online
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Subjects

• Adult
• Aged
• Amitriptyline
• Double-Blind Method
• Electroencephalography
• Fatigue
• Female
• Fibromyalgia
• Humans
• Male
• Middle Aged
• Placebos
• Sleep
• Sleep Disorders
• Treatment Outcome

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Authors

• Harvey Moldofsky
• Herbert W Harris
• W Tad Archambault
• Terence Kwong
• Seth Lederman

Publication date

2011-12-02

Journal

Journal topics

• Arthritis
• Rheumatic Diseases

Language

Eng.

Copyright

The Journal of rheumatology

Sleep Disorders Clinics, Centre for Sleep and Chronobiology, University of Toronto, Toronto, Ontario, Canada. h.moldofsky [at] utoronto.ca

Release reference

J Rheumatol. 2011 Dec;38(12):2653-63

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