Fibrosis of pulmonary vascular remodeling in carotid artery-jugular vein shunt pulmonary artery hypertension model of rats.

Abstract

CA-JV shunt model of rats was a well-established PAH animal model simulating congenital heart disease with systemic-pulmonary shunt.

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Subjects

• Animals
• Arterioles
• Arteriovenous Shunt, Surgical
• Carotid Artery, Common
• Disease Models, Animal
• Fibrosis
• Gene Expression Regulation
• Hemodynamics
• Hypertension, Pulmonary
• Jugular Veins
• Male
• Pulmonary Artery
• RNA, Messenger
• Rats
• Rats, Sprague-Dawley
• Receptors, Transforming Growth Factor beta
• Transforming Growth Factor beta1

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Authors

• Mai Xiong
• Jian-Ping Yao
• Zhong-Kai Wu
• Bing Liao
• Ying-Jie Liang
• Xi Zhang
• Zhi-Ping Wang

Publication date

2012-03-01

Journal

Journal topics

• Cardiac Surgical Procedures
• Thoracic Surgery

Language

Eng.

Copyright

Department of Cardiac Surgery, the 1st Affiliated Hospital of Sun Yat-Sen University, Guangzhou, PR China.

Release reference

Eur J Cardiothorac Surg. 2012 Jan;41(1):162-6

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