Activated c-MET has pleiotropic effects on multiple cancer-promoting signaling pathways and may play a critical role in driving tumor cell growth and survival. INCB28060 is a potent and selective c-MET kinase inhibitor that may have therapeutic potential in cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research
Incyte Corporation, Wilmington, Delaware 19880, USA. xliu [at] incyte.com
Clin Cancer Res. 2011 Nov;17(22):7127-38
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