Salvage stereotactic radiosurgery for breast cancer brain metastases: outcomes and prognostic factors.

Abstract

In patients with good Karnofsky performance status, salvage SRS for breast cancer brain metastases is a reasonable treatment option, given an associated median survival in excess of 9 months. Furthermore, patients with HER2-positive tumors at diagnosis or stable extracranial disease at the time of SRS have an improved clinical course, with median survival of >1 year.

Full Text

• DOI - Cancer (DOI)
• John Wiley & Sons, Inc. - full-text online
• Swets Information Services - full-text online
• OhioLINK Electronic Journal Center - full-text online
• EBSCO - full-text online

Subjects

• Adult
• Brain Neoplasms
• Breast Neoplasms
• Female
• Humans
• Middle Aged
• Prognosis
• Radiosurgery
• Retrospective Studies
• Salvage Therapy
• Treatment Outcome

Similar articles

• The efficacy and limitations of stereotactic radiosurgery as a salvage treatment after failed whole brain radiotherapy for brain metastases. (2013-05-10)
• Stereotactic radiosurgery for the treatment of brain metastases; results from a single institution experience. (2013-02-09)
• Survival among patients with 10 or more brain metastases treated with stereotactic radiosurgery. (2013-05-10)
• Predictors of survival in contemporary practice after initial radiosurgery for brain metastases. (2012-08-14)
• Salvage stereotactic radiosurgery effectively treats recurrences from whole-brain radiation therapy. (2008-10-09)
• The role of stereotactic radiosurgery for multiple brain metastases in stable systemic disease: a review of the literature. (2013-05-02)
• Validation of Recursive Partitioning Analysis and Diagnosis-Specific Graded Prognostic Assessment in patients treated initially with radiosurgery alone. (2012-12-04)
• Fractionated Stereotactic Radiosurgery for Large Brain Metastases. (2013-04-03)
• Stereotactic radiosurgery for single brainstem metastases: the cleveland clinic experience. (2010-09-13)

Authors

• Paul J Kelly
• Nancy U Lin
• Elizabeth B Claus
• Eudocia C Quant
• Stephanie E Weiss
• Brian M Alexander

Publication date

2012-04-10

Journal

Journal topics

• Neoplasms

Language

Eng.

Copyright

Cancer

Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts, USA. paulj.kelly [at] hse.ie

Release reference

Cancer. 2012 Apr;118(8):2014-20

Related books

• Books of Brain Neoplasms
• Books of Breast Neoplasms
• Books of Neoplasms
• Books of Prognosis
• Books of Radiosurgery
• Books of Retrospective Studies
• Books of Salvage Therapy
• Books of Treatment Outcome