Prospective, repeated characterization of a birth cohort demonstrated that allergic sensitization precedes HRV wheezing and that the converse is not true.
This sequential relationship and the plausible mechanisms by which allergic sensitization can lead to more severe HRV-induced lower respiratory illnesses support a causal role for allergic sensitization in this developmental pathway. Therefore, therapeutics aimed at preventing allergic sensitization may modify virus-induced wheezing and the development of asthma.
2012-02-02
Eng.
American journal of respiratory and critical care medicine
University of Wisconsin, Madison, 53792, USA. djj [at] medicine.wisc.edu
Am J Respir Crit Care Med. 2012 Feb;185(3):281-5
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