Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy.

Abstract

Differentiation stage divides allergen-specific CD4(+) T cells into 2 distinct subpopulations with unique functional properties and different fates during SIT.

Full Text

• DOI - The Journal of allergy and clinical immunology (DOI)
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Subjects

• Adult
• Allergens
• Antigens, Plant
• CD4-Positive T-Lymphocytes
• Cell Differentiation
• Cytokines
• Desensitization, Immunologic
• Humans
• Immunoglobulin E
• Middle Aged
• Plant Proteins
• Pollen
• Rhinitis, Allergic, Seasonal
• Skin Tests

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Authors

• Erik Wambre
• Jonathan H DeLong
• Eddie A James
• Rebecca E LaFond
• David Robinson
• William W Kwok

Publication date

2012-01-30

Journal

Journal topics

• Allergy and Immunology
• Hypersensitivity

Language

Eng.

Copyright

The Journal of allergy and clinical immunology

Benaroya Research Institute at Virginia Mason, Seattle, Wash 98101, USA.

Release reference

J Allergy Clin Immunol. 2012 Feb;129(2):544-51, 551.e1-7

Related books

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