Clinicopathologic and immunohistochemical features of pigmented Basal cell carcinomas of the eyelids.

Abstract

Only 1 of 6 lesions was uniformly clinically pigmented, whereas the other 5 were only focally brown-black. The clinical pigmentation was imparted by varying densities and distributions of melanocytes with arborizing dendrites, which were present in all BCCs. Melanophages within the stroma and basaloid cell melanization also contributed to pigmentation.

No behavioral or biologic differences in pBCC were documented compared with clinically nonpigmented lesions.

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Subjects

• Adult
• Aged
• Aged, 80 and over
• Carcinoma, Basal Cell
• Eyelid Neoplasms
• Female
• Humans
• Immunoenzyme Techniques
• Male
• Middle Aged
• Neoplasm Proteins
• Nevus, Pigmented
• Retrospective Studies
• Skin Neoplasms
• Tumor Markers, Biological

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Authors

• Maria Kirzhner
• Frederick A Jakobiec

Publication date

2012-01-23

Journal

Journal topics

• Ophthalmology

Language

Eng.

Copyright

David G. Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Room 321, 243 Charles St, Boston, MA 02114, USA.

Release reference

Am J Ophthalmol. 2012 Feb;153(2):242-252.e2

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