Apolipoprotein B100 is a better treatment target than calculated LDL and non-HDL cholesterol in statin-treated patients.

Abstract

ApoB offers a more consistent treatment target independent of hypertriglyceridaemia and would obviate technical problems related to high triglycerides.

Full Text

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Subjects

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Analysis of Variance
• Apolipoprotein B-100
• Cholesterol, HDL
• Cholesterol, LDL
• Clinical Trials as Topic
• Fluorobenzenes
• Heptanoic Acids
• Humans
• Hydroxymethylglutaryl-CoA Reductase Inhibitors
• Hyperlipidemias
• Middle Aged
• Pravastatin
• Pyrimidines
• Pyrroles
• Reference Values
• Regression Analysis
• Simvastatin
• Sulfonamides
• Triglycerides
• Young Adult

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Authors

• Handrean Soran
• Michael W France
• See Kwok
• Sanjaya Dissanayake
• Valentine Charlton-Menys
• Nahla N Younis
• Paul N Durrington

Publication date

2011-11-02

Journal

Journal topics

• Biochemistry
• Chemistry, Clinical

Language

Eng.

Copyright

Cardiovascular Research Group, School of Biomedicine, Core Technology Facility, 3rd Floor, University of Manchester, 46 Grafton Street, Manchester M13 9NT, UK. Handrean.Soran [at] cmft.nhs.uk

Release reference

Ann Clin Biochem. 2011 Nov;48(Pt 6):566-71

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