Early versus delayed autologous transplantation after immunomodulatory agents-based induction therapy in patients with newly diagnosed multiple myeloma.

Abstract

The current results indicated that, in transplantation-eligible patients who receive IMiDs as initial therapy followed by early stem cell mobilization, delayed SCT results in similar overall survival compared with early SCT. It is noteworthy that an excellent 4-year survival rate of >80% was observed among transplantation-eligible patients who received initial therapy with LD regardless of the timing of transplantation.

Full Text

• DOI - Cancer (DOI)
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Subjects

• Adult
• Aged
• Female
• Hematopoietic Stem Cell Transplantation
• Humans
• Immunologic Factors
• Male
• Middle Aged
• Multiple Myeloma
• Survival Rate
• Transplantation, Autologous

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Authors

• Shaji K Kumar
• Martha Q Lacy
• Angela Dispenzieri
• Francis K Buadi
• Suzanne R Hayman
• David Dingli
• Francesca Gay
• Shirshendu Sinha
• Nelson Leung
• William Hogan
• S Vincent Rajkumar
• Morie A Gertz

Publication date

2012-03-05

Journal

Journal topics

• Neoplasms

Language

Eng.

Copyright

Cancer

Divisions of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. kumar.shaji [at] mayo.edu

Release reference

Cancer. 2012 Mar;118(6):1585-92

Related books

• Books of Hematopoietic Stem Cell Transplantation
• Books of Immunologic Factors
• Books of Multiple Myeloma
• Books of Neoplasms
• Books of Survival Rate
• Books of Transplantation, Autologous