Lipid resuscitation of bupivacaine toxicity: long-chain triglyceride emulsion provides benefits over long- and medium-chain triglyceride emulsion.

Abstract

LCT emulsion may be superior to LCT/MCT emulsion in treating bupivacaine-related cardiotoxicity as it was associated with fewer recurrences of asystole after resuscitation and lower myocardial bupivacaine concentrations.

Full Text

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Subjects

• Analysis of Variance
• Anesthetics, Local
• Animals
• Bronchodilator Agents
• Bupivacaine
• Disease Models, Animal
• Emulsions
• Epinephrine
• Fat Emulsions, Intravenous
• Heart Arrest
• Lipids
• Male
• Phospholipids
• Rats
• Rats, Sprague-Dawley
• Resuscitation
• Soybean Oil
• Triglycerides

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Authors

• Zhengqian Li
• Yun Xia
• Xiaoxi Dong
• Hongfei Chen
• Fangfang Xia
• Xianqin Wang
• Huimin Dong
• Zhousheng Jin
• Xili Ding
• Thomas J Papadimos
• Xuzhong Xu

Publication date

2011-11-29

Journal

Journal topics

• Anesthesiology

Language

Eng.

Copyright

Anesthesiology

Department of Anesthesiology, The First Affiliated Hospital, Wenzhou Medical College, Zhejiang, China.

Release reference

Anesthesiology. 2011 Dec;115(6):1219-28

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