Deletion of estrogen receptor beta accelerates early stage of bone healing in a mouse osteotomy model.


Abstract

The fracture healing in KO mice was enhanced in the early stage of neovascularization and the middle stage of endochondral ossification, but not by the end of healing.

Blockade of ERbeta can be considered as another therapeutic strategy for osteoporotic fracture and non-union fracture.


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Publication date

2012-01-02


Journal

Osteoporosis international
Osteoporos Int (1433-2965)

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Language

Eng.


Copyright

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Musculoskeletal Research Laboratory, Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, China.


Release reference

Osteoporos Int. 2012 Jan;23(1):377-89



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