Our findings suggest that apoE reduces atherosclerosis in the setting of hyperlipidemia by increasing plasma apoA1-HDL that likely contribute to reduce intracellular lipid accumulation and thereby the activation of circulating leukocytes and the vascular endothelium.
Arteriosclerosis, thrombosis, and vascular biology
Department of Surgery, University of California San Francisco and VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA.
Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):264-72
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