Thrombotic thrombocytopenic purpura.

Abstract

In 1924, Dr Eli Moschcowitz described a 16-year-old adolescent girl with abrupt onset of petechiae, hemolytic anemia, followed by paralysis, coma, and death.

Autopsy showed widespread hyaline thrombi in the terminal arterioles and capillaries of various organs.

The syndrome described by Moschowitz is now known as thrombotic thrombocytopenic purpura.

Full Text

• DOI - Pediatric emergency care (DOI)
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Subjects

• ADAM Proteins
• Child
• Diagnosis, Differential
• Disseminated Intravascular Coagulation
• Hemolytic-Uremic Syndrome
• Humans
• Immunosuppressive Agents
• Plasma
• Plasma Exchange
• Platelet Transfusion
• Purpura, Thrombotic Thrombocytopenic

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Authors

• Alex Koyfman
• Elizabeth Brém
• Vincent W Chiang

Publication date

2011-11-09

Journal

Journal topics

• Emergencies
• Emergency Medicine

Language

Eng.

Copyright

Pediatric emergency care

Department of Emergency Medicine, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, MA 02115, USA. akoyfman [at] partners.org

Release reference

Pediatr Emerg Care. 2011 Nov;27(11):1085-8; quiz 1089-90

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