Factors and comorbidities associated with first neuropsychiatric event in systemic lupus erythematosus: does a risk profile exist? A large multicentre retrospective cross-sectional study on 959 Italian patients.

Abstract

In SLE, NP involvement and aPLs were confirmed as closely related. Furthermore, other modifiable generic risk factors, such as hypertension, carotid vasculopathy and dyslipidaemia, appeared to be related to the occurrence of cerebral vascular accident (CVA) and cognitive dysfunctions, suggesting the need for a more intensive preventive strategy to optimize the management of NP lupus.

Full Text

• DOI - Rheumatology (Oxford, England) (DOI)
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Subjects

• Adult
• Antibodies, Antiphospholipid
• Antiphospholipid Syndrome
• Biological Markers
• Comorbidity
• Epidemiologic Methods
• Female
• Headache Disorders
• Humans
• Italy
• Lupus Vasculitis, Central Nervous System
• Male
• Mental Disorders
• Middle Aged
• Prognosis
• Stroke

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Authors

• Marcello Govoni
• Stefano Bombardieri
• Alessandra Bortoluzzi
• Luisa Caniatti
• Cinzia Casu
• Fabrizio Conti
• Salvatore De Vita
• Andrea Doria
• Ilaria Farina
• Gianfranco Ferraccioli
• Elisa Gremese
• Elisa Mansutti
• Marta Mosca
• Melissa Padovan
• Matteo Piga
• Angela Tincani
• Mar

Publication date

2011-12-22

Journal

Journal topics

• Rheumatic Diseases

Language

Eng.

Copyright

Rheumatology (Oxford, England)

Department of Clinical and Experimental Medicine, Section of Rheumatology, University of Ferrara, C.so Giovecca 203, 44121 Ferrara, Italy. gvl [at] unife.it

Release reference

Rheumatology (Oxford). 2012 Jan;51(1):157-68

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