Childhood-onset disease carries a higher risk of low bone mineral density in an adult population of systemic lupus erythematosus.

Abstract

In adult SLE patients, childhood-onset disease carries a higher risk of osteoporosis, which may possibly be related to a higher cumulative dose of glucocorticoids used for more active disease and failure to achieve a normal peak bone mass during puberty.

Full Text

• DOI - Rheumatology (Oxford, England) (DOI)
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Subjects

• Absorptiometry, Photon
• Adolescent
• Adult
• Age of Onset
• Body Mass Index
• Bone Density
• Cross-Sectional Studies
• Female
• Glucocorticoids
• Hip
• Humans
• Incidence
• Linear Models
• Lupus Erythematosus, Systemic
• Male
• Middle Aged
• Osteoporosis
• Risk Factors
• Severity of Illness Index
• Spine
• Young Adult

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Authors

• Chi Chiu Mok
• Sik Nin Wong
• Kwok Man Ma

Publication date

2012-02-20

Journal

Journal topics

• Rheumatic Diseases

Language

Eng.

Copyright

Rheumatology (Oxford, England)

Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong, SAR, China. ccmok2005 [at] yahoo.com

Release reference

Rheumatology (Oxford). 2012 Mar;51(3):468-75

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