In adult SLE patients, childhood-onset disease carries a higher risk of osteoporosis, which may possibly be related to a higher cumulative dose of glucocorticoids used for more active disease and failure to achieve a normal peak bone mass during puberty.
Rheumatology (Oxford, England)
Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong, SAR, China. ccmok2005 [at] yahoo.com
Rheumatology (Oxford). 2012 Mar;51(3):468-75
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