MicroRNA alterations of pancreatic intraepithelial neoplasias.

Abstract

Many miRNAs undergo aberrant expression in PanIN lesions and are likely to be important in the development of PDAC. The miRNAs, such as miR-196b, whose expression is limited to PanIN-3 lesions or pancreatic cancers could be useful as diagnostic markers.

Full Text

DOI - Clinical cancer research : an official journal of the American Association for Cancer Research (DOI)
HighWire Press - full-text online

Subjects

Similar articles

BRCA2 dysfunction promotes malignant transformation of pancreatic intraepithelial neoplasia. (2011-05-01)
Serine protease inhibitor Kazal type 1 and epidermal growth factor receptor are expressed in pancreatic tubular adenocarcinoma, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia. (2013-03-12)
The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia. (2008-10-22)
CC chemokine receptor 9 enhances proliferation in pancreatic intraepithelial neoplasia and pancreatic cancer cells. (2010-01-29)
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia. (2002-11-04)
Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor. (2007-08-02)
PAM4-reactive MUC1 is a biomarker for early pancreatic adenocarcinoma. (2007-12-20)
Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis. (2012-09-12)
Class III beta-tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia. (2007-09-20)

Authors

Publication date

2012-02-16

Journal

Clinical cancer research
Clin Cancer Res (1078-0432)

Journal topics

Language

Eng.

Copyright

Clinical cancer research : an official journal of the American Association for Cancer Research

Department of Pathology, Oncology, and Medicine, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

Release reference

Clin Cancer Res. 2012 Feb;18(4):981-92

Related books

Español | English

© Galenicom 1999-2013