Our findings suggest that HRV infections in children with asthma are specifically associated with acute wheezing, and that type III IFN-λ(1) responses mediate exacerbations caused by HRV. Modulation of IFN- λ(1) should be studied as a therapeutic target for exacerbations caused by HRV.
American journal of respiratory and critical care medicine
Department of Pediatrics, Vanderbilt University, Nashville, TN 37232, USA.
Am J Respir Crit Care Med. 2012 Mar;185(5):508-16
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