Autoimmune autonomic ganglionopathy with reversible cognitive impairment.

Abstract

Reversible cognitive impairment is independently associated with both orthostatic hypotension and elevated nicotinic acetylcholine receptor autoantibodies, thereby expanding the clinical spectrum of autonomic ganglionopathy and, in so doing, providing an additional treatable cause of cognitive impairment.

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Subjects

• Analysis of Variance
• Antibodies
• Attention
• Autoimmune Diseases of the Nervous System
• Blood Pressure
• Cohort Studies
• Female
• Ganglia, Autonomic
• Heart Rate
• Humans
• Hypotension, Orthostatic
• Middle Aged
• Mild Cognitive Impairment
• Neuropsychological Tests
• Plasma Exchange
• Psychomotor Performance
• Receptors, Cholinergic

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Authors

• Christopher H Gibbons
• Justin Centi
• Steven Vernino
• Roy Freeman

Publication date

2012-04-11

Journal

Journal topics

• Neurology

Language

Eng.

Copyright

Department of Neurology, Beth Israel Deaconess Medical Center, 1 Deaconess Rd., Boston, MA 02215, USA.

Release reference

Arch Neurol. 2012 Apr;69(4):461-6

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