IL-31 regulates differentiation and filaggrin expression in human organotypic skin models.

Abstract

Our study suggests that IL-31 is an important regulator of keratinocyte differentiation and demonstrates a link between the presence of IL-31 in skin, as found in patients with AD, and filaggrin expression.

Full Text

• DOI - The Journal of allergy and clinical immunology (DOI)
• Swets Information Services - full-text online
• Ovid Technologies, Inc. - full-text online
• OhioLINK Electronic Journal Center - full-text online
• MD Consult - full-text online
• Elsevier Science - full-text online
• EBSCO - full-text online

Subjects

• Cell Differentiation
• Cell Line
• Cells, Cultured
• Dermatitis, Atopic
• Humans
• Interleukins
• Intermediate Filament Proteins
• Keratinocytes
• Recombinant Proteins
• Skin

Similar articles

• Cytokine modulation of atopic dermatitis filaggrin skin expression. (2009-09-01)
• Altered mRNA and protein expression of filaggrin in the skin of a canine animal model for atopic dermatitis. (2013-03-16)
• Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis. (2013-01-25)
• Decreased expression of filaggrin in atopic skin. (1997-01-02)
• IL-25 Enhances HSV-1 Replication by Inhibiting Filaggrin Expression, and Acts Synergistically with TH2 Cytokines to Enhance HSV-1 Replication. (2013-05-08)
• Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death. (2012-12-11)
• Cytokine modulation of atopic dermatitis filaggrin skin expression. (2007-07-03)
• Filaggrin mutations and the skin. (2012-09-10)
• Expression of Caspase 14 and Filaggrin in Oral Squamous Carcinoma. (2013-05-04)

Authors

• Christian Cornelissen
• Yvonne Marquardt
• Katharina Czaja
• Jörg Wenzel
• Jorge Frank
• Juliane Lüscher-Firzlaff
• Bernhard Lüscher
• Jens M Baron

Publication date

2012-01-30

Journal

Journal topics

• Allergy and Immunology
• Hypersensitivity

Language

Eng.

Copyright

The Journal of allergy and clinical immunology

Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen, Germany.

Release reference

J Allergy Clin Immunol. 2012 Feb;129(2):426-33, 433.e1-8

Related books

• Books of Allergy and Immunology
• Books of Cell Differentiation
• Books of Cell Line
• Books of Cells, Cultured
• Books of Dermatitis, Atopic
• Books of Hypersensitivity
• Books of Interleukins
• Books of Intermediate Filament Proteins
• Books of Keratinocytes
• Books of Recombinant Proteins
• Books of Skin