Intensity-modulated radiotherapy for pancreatic adenocarcinoma.

Abstract

Survival for patients with pancreatic cancer remains poor. A small percentage of adjuvant patients have durable disease control, and with improved therapies, this proportion will increase.

Systemic therapy offers the greatest opportunity.

The present results have demonstrated that IMRT is well tolerated.

Compared with those who received three-dimensional conformal radiotherapy in previously reported prospective clinical trials, patients with pancreatic adenocarcinoma treated with IMRT in our series had improved acute toxicity.

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Subjects

• Adenocarcinoma
• Aged
• Aged, 80 and over
• Antimetabolites, Antineoplastic
• Chemotherapy, Adjuvant
• Deoxycytidine
• Disease-Free Survival
• Female
• Fluorouracil
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local
• Pancreatic Neoplasms
• Radiotherapy Dosage
• Radiotherapy, Intensity-Modulated
• Retrospective Studies
• Survival Rate

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Authors

• Jonathan A Abelson
• James D Murphy
• Ann Yuriko Minn
• Melody Chung
• George A Fisher
• James M Ford
• Pamela Kunz
• Jeffrey A Norton
• Brendan C Visser
• George A Poultsides
• Albert C Koong
• Daniel T Chang

Publication date

2012-03-05

Journal

Journal topics

• Radiobiology

Language

Eng.

Copyright

Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA.

Release reference

Int J Radiat Oncol Biol Phys. 2012 Mar;82(4):e595-601

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