Reduced medial prefrontal responses to social interaction images in remitted depression.


Abstract

In the absence of current symptoms, individuals with remitted major depressive disorder showed reduced frontopolar processing of stimuli showing social interactions, a reduction not seen for stimuli showing individual successes and failures and, therefore, not simply an effect of emotional valence.

These results suggest a specific trait abnormality in social emotional processing associated with vulnerability to depression, which may have implications for understanding social cognition mechanisms and for developing effective psychological therapies.


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Publication date

2012-01-03


Journal

Archives of general psychiatry
Arch Gen Psychiatry (1538-3636)

Journal topics


Language

Eng.


Copyright

Archives of general psychiatry

Neuroscience and Psychiatry Unit, University of Manchester, Manchester, England. Rebecca.elliott [at] manchester.ac.uk


Release reference

Arch Gen Psychiatry. 2012 Jan;69(1):37-45



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