Effects of low molecular weight heparin and heparin-binding epidermal growth factor on human trophoblast in first trimester.

Abstract

The LMWH exerts a cytoprotective effect by regulating trophoblast proliferation, invasion, and differentiation.

The HB-EGF is an important factor in the effects of LMWH on trophoblast function.

Full Text

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Subjects

• Cell Differentiation
• Cell Movement
• Cell Proliferation
• Cells, Cultured
• Chorionic Gonadotropin
• Cytoprotection
• Dose-Response Relationship, Drug
• Enoxaparin
• Female
• Humans
• Intercellular Signaling Peptides and Proteins
• Pregnancy
• Pregnancy Trimester, Third
• Trophoblasts

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Authors

• Ying Chen
• Xiao-Xia Wu
• Jian-ping Tan
• Mei-lan Liu
• Ying-lin Liu
• Jian-Ping Zhang

Publication date

2012-03-02

Journal

Journal topics

• Fertility
• Infertility

Language

Eng.

Copyright

Fertility and sterility

Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.

Release reference

Fertil Steril. 2012 Mar;97(3):764-70

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