Cigarette smoke inhibits dynamic ciliary beat frequency in pediatric adenoid explants.


Abstract

CBF of adenoid explants increases when stimulated with isoproterenol and methacholine.

Ex vivo and in vitro smoke exposure blunted ciliostimulation of CBF in adenoid explants.

Smoke exposure impairs ciliary function in the pediatric airway and could potentially contribute to disorders such as chronic rhinosinusitis and chronic otitis media.


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Publication date

2012-04-03


Journal

Otolaryngology--head and neck surgery
Otolaryngol Head Neck Surg (1097-6817)

Journal topics


Language

Eng.


Copyright

Medical University of South Carolina, Department of Otolaryngology-Head and Neck Surgery, Charleston, South Carolina 29403, USA.


Release reference

Otolaryngol Head Neck Surg. 2012 Apr;146(4):659-63



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