These two cases can be added to the other 15 cases of HPV-positive primary oropharyngeal SCC identified in our department from 1956 to 1969. When determining the incidence of HPV-positive oropharyngeal SCC before the 1970s, a correction factor of about +13% (2/15) accounting for modern pathologic workup of SCCUP during the last couple of decades may be appropriate.
University of Pittsburgh Medical Center, Department of Pathology, Pittsburgh, Pennsylvania 15261, USA.
Laryngoscope. 2012 Apr;122(4):793-6
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