High expression of luteinizing hormone receptors messenger RNA by human cumulus granulosa cells is in correlation with decreased fertilization.

Abstract

The LHR expression in small follicles obtained in IVM suggests a role for hCG administration during IVM procedures.

Overexpression of LHR in cumulus GCs of MII oocytes may signal malfunction of oocytes and low fertilization capacity.

Full Text

• DOI - Fertility and sterility (DOI)
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Subjects

• Adult
• Analysis of Variance
• Cells, Cultured
• Cumulus Cells
• Female
• Fertility Agents, Female
• Fertilization in Vitro
• Humans
• In Vitro Oocyte Maturation Techniques
• Ovulation Induction
• Pregnancy
• RNA, Messenger
• Receptors, LH
• Time Factors
• Treatment Outcome
• Up-Regulation

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Authors

• Ettie Maman
• Yuval Yung
• Alon Kedem
• Gil M Yerushalmi
• Sarah Konopnicki
• Berta Cohen
• Jehoshua Dor
• Ariel Hourvitz

Publication date

2012-03-02

Journal

Journal topics

• Fertility
• Infertility

Language

Eng.

Copyright

Fertility and sterility

IVF Unit and Fertility Research Laboratory, Sheba Medical Center, Tel Hashomer, Israel.

Release reference

Fertil Steril. 2012 Mar;97(3):592-8

Related books

• Books of Analysis of Variance
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• Books of In Vitro Oocyte Maturation Techniques
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