These results demonstrate an important role of the calpain/calpastatin system in coagulation/inflammation pathways during sepsis, because calpain inhibition is associated with less severe disseminated intravascular coagulation and better overall outcomes in sepsis.
American journal of respiratory and critical care medicine
Université Pierre et Marie Curie, Paris VI, UMR S 702, Paris, France. larazafrani [at] hotmail.com
Am J Respir Crit Care Med. 2012 Apr;185(7):744-55
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