Combination of two urinary biomarkers predicts acute kidney injury after adult cardiac surgery.

Abstract

When urinary L-FABP and NAG are combined, they can detect AKI adequately, even in a heterogeneous population of adult post-cardiac surgery AKI. Combining 2 markers with different sensitivity and specificity presents a reasonable strategy to improve the diagnostic performance of biomarkers.

Full Text

• DOI - The Annals of thoracic surgery (DOI)
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Subjects

• Acetylglucosaminidase
• Acute Kidney Injury
• Aged
• Area Under Curve
• Biological Markers
• Cardiac Surgical Procedures
• Coronary Artery Bypass
• Creatinine
• Fatty Acid-Binding Proteins
• Female
• Heart Valves
• Humans
• Male
• Middle Aged
• Postoperative Complications
• Predictive Value of Tests
• Prospective Studies
• ROC Curve
• Risk Assessment
• Sensitivity and Specificity

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Authors

• Daisuke Katagiri
• Kent Doi
• Kenjiro Honda
• Kousuke Negishi
• Toshiro Fujita
• Motoyuki Hisagi
• Minoru Ono
• Takehiro Matsubara
• Naoki Yahagi
• Masao Iwagami
• Takayasu Ohtake
• Shuzo Kobayashi
• Takeshi Sugaya
• Eisei Noiri

Publication date

2012-01-24

Journal

Journal topics

• Thoracic Diseases

Language

Eng.

Copyright

The Annals of thoracic surgery

Department of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.

Release reference

Ann Thorac Surg. 2012 Feb;93(2):577-83

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